Homosalate

Also Known As:

  • 3,3,5-Trimethylcyclohexyl 2-hydroxybenzoate

What is it?
Homosalate is an organic compound commonly used in sunscreens. It is a chemical UV filter that helps protect the skin from the harmful effects of ultraviolet (UV) radiation. Homosalate absorbs UVB rays, which are primarily responsible for causing sunburn and contributing to skin cancer.

What Makes it Different?
Homosalate is unique due to its specific chemical structure, which includes a salicylate group. This structure allows it to absorb UVB rays effectively. Additionally, it acts as a solvent for other UV filters, enhancing their stability and effectiveness. Unlike some other UV filters, homosalate is known for its low risk of causing allergic reactions and its ability to reduce UV-induced redness.

Where Does it Come From?
Homosalate is synthesized through the Fischer–Speier esterification process, which involves the reaction of salicylic acid with 3,3,5-trimethylcyclohexanol. The latter is a hydrogenated derivative of isophorone. This synthetic process allows for the production of homosalate in large quantities for use in various skincare products.

Where is it Used?
Homosalate is primarily used in sunscreens and other sun protection products. It is often found in formulations with higher SPF ratings, as it provides effective UVB protection. Additionally, it is used in combination with other UV filters, such as avobenzone, to offer broad-spectrum protection. Homosalate is also used in some moisturizers and makeup products that include sun protection.

Is it Sustainable?
The sustainability of homosalate is a complex issue. While it is effective in protecting the skin from UV damage, its production and use raise several environmental and health concerns.

Sustainable Issues Related to its Production:

  1. Environmental Impact: The production of homosalate involves chemical processes that can generate waste and emissions, contributing to environmental pollution. Additionally, the presence of homosalate in water bodies, due to its use in sunscreens, can have adverse effects on aquatic life.
  2. Health Concerns: Although homosalate is considered safe for use in cosmetics, there are ongoing studies to better understand its potential systemic absorption and long-term effects on human health. Some in vitro studies have shown that homosalate can act as an endocrine disruptor, but these effects have not been observed in vivo.
  3. Regulatory Scrutiny: Homosalate is currently undergoing further safety and toxicology testing by regulatory bodies such as the FDA. This testing aims to ensure that the ingredient is safe for long-term use and to address any potential health risks associated with its absorption into the body.

In summary, while homosalate is an effective and widely used UV filter, its production and use come with certain sustainability challenges that need to be addressed to minimize its environmental and health impacts.